The aim of the MoxiMultiDoseMod project is to generate further data to expand the approved label for moxidectin and to support its registration and policy decisions for the adoption of moxidectin-based treatment strategies for onchocerciasis control and elimination in onchocerciasis endemic countries. 

MoxiMultiDoseMod includes the following program of work:

• a paediatric dose-finding study

• two phase 3b trials comparing efficacy and safety of single dose and annual and biannual doses of moxidectin or ivermectin treatment; and

• mathematical modelling of moxidectin and ivermectin based elimination strategies to support country policy decisions.

See “Work Packages” for further details on the clinical trials.